The most prevalent perils facing the mainland United States may come not from the east or the west, but from the south, an area of the globe often overlooked in the talk about global security. Unlike other U.S. geographic combatant command theaters, the U.S. Southern Command area of responsibility has no wars and no major military-power threats. It does, however, encompass hundreds of billions of dollars worth of illicit trafficking every year. But those troubles are only part of the story. The command also serves as a model for the power of interagency collaboration and neighbor-to-neighbor support, as many countries in the region have been able to grow their democracy, reduce the size and influence of terrorist groups and offer aid to nations hit hard by natural disasters. Relationships and technology can hold the answers for bringing stability to an area that historically has been unsettled.