Scientists at Sandia National Laboratories, Albuquerque, New Mexico, are conducting ground-breaking research into super-small structures that has led to prototype devices such as ultraminiaturized chemical sensors and analyzers, tiny medical devices, super-strong alloys, and catalysts for destroying hazardous materials. Future applications could include filters that selectively admit or seal out substances through molecule-sized valves, medical devices that precisely monitor patient health and deliver exact doses of medication based on that data, and clothing that knows when the wearer is hot or cold and then admits air or becomes an insulator accordingly.